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HOUSE_OVERSIGHT_029539

Dr. Stem Cell

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Alan Trounson, California's Dr. Stem Cell -- latimes.com Page 1 of 4 
latimes.com/news/opinion/commentary/la-oe-0529-morrison-trounson-20130529,0,7837846.column 
latimes.com 
Patt Morrison Asks 
Alan Trounson, California's Dr. Stem Cell 
As president of the California Institute for Regenerative Medicine, the Australian 
is helping guide the state to a high-tech medical future. 
Patt Morrison 
May 29, 2013 
In 2004, with President George W. Bush dead set 
against stem cell research, California just went ahead 1> 
and did it. Voters made stem cell research a state 
constitutional right, and endorsed $3 billion in bond 
sales for 10 years to cement the deal. CIRM, the 
California Institute for Regenerative Medicine created 
under Proposition 71, has become a world center for 
stem cell research, and its president is Australian Alan 
Trounson, a pioneer in in vitro fertilization. As 
Proposition 71 approaches its 10-year anniversary, 
Trounson offers a prognosis. 
It's been almost 10 years since California funded 
what may be the world's biggest stem cell research 
program. What are you up to? 
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We are working hard to get six or seven projects to clinical trials. We have more than 70 [total] 
programs moving [toward] clinical trials. It's a lot of work to chaperon. 
I'll give you three examples: one, linking genetics, or genomics work, to stem cells, integrating the 
two. We're going to create a center in California that will bring a lot of [genetics] studies and clinical 
work to a new level. 
Secondly, we've set up a structure for banking the 3,000 cell lines from "induced pluripotent stem 
cells" that we turn into the equivalent of embryonic stem cells. We call them IPS cells. You take a 
skin cell or blood cell and convert it to the equivalent of an embryonic stem cell. 
We've also taken samples from patients with complex diseases, and we're ba

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